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Official GuidanceUnited StatesMar 18, 2026

Biosafety in Microbiological and Biomedical Laboratories (BMBL), 6th Edition

Centers for Disease Control and Prevention / National Institutes of Health

The sixth edition of BMBL is advisory U.S. biosafety guidance built around protocol-driven risk assessment and best practices for safe work in biomedical and clinical laboratories; it is not itself a regulatory document.

BiosafetyClinical laboratory biosafetyRisk assessment
Official GuidanceInternationalJun 21, 2024

Laboratory Biosecurity Guidance

World Health Organization

WHO guidance applying a risk- and evidence-based approach to laboratory biosecurity, including governance, institutional responsibilities, regulatory oversight and management of high-consequence biological material, technology and information.

Official GuidanceInternationalDec 21, 2020

Laboratory biosafety manual, 4th edition

World Health Organization

WHO's fourth-edition Laboratory Biosafety Manual uses an evidence- and risk-based approach and serves as a global reference for laboratory biosafety frameworks and practices.

BiosafetyLaboratory securityRisk assessment
Official GuidanceInternationalDec 20, 2020

Laboratory Biosafety Manual, 4th Edition: Risk Assessment

World Health Organization

WHO monograph supporting risk-based laboratory biosafety decisions and proportionate control selection as part of the Laboratory Biosafety Manual fourth-edition suite.

Binding / RegulatoryInternationalMar 26, 1975

Convention on the Prohibition of the Development, Production and Stockpiling of Bacteriological (Biological) and Toxin Weapons and on their Destruction

United Nations Office for Disarmament Affairs

The Biological Weapons Convention prohibits biological and toxin weapons and requires States Parties to translate its commitments into national measures. UNODA maintains the official Convention text and implementation resources.

Biological Weapons ConventionBiological nonproliferationNational implementation
Official GuidanceInternationalDate not specified

Biological Weapons Convention Confidence-Building Measures

United Nations Office for Disarmament Affairs

UNODA information on the Biological Weapons Convention confidence-building measures process, which supports transparency and confidence among States Parties through annual information exchange.